Nurofen is a brand of range of pain-relief medication containing ibuprofen made by the English - Dutch company Reckitt Benckiser. [1] Introduced in 1983, the Nurofen brand was acquired following Reckitt Benckiser's acquisition of Boots healthcare international in 2005 for £1.93 billion, which included Nurofen, Strepsils, and Clearasil. [2] Explore the Nurofen pain relief range, with products for period pain, migraines & cold & flu. Shop at boots.com or Click & Collect in store. Nurofen is a non-selective COX inhibitor and hence, it inhibits the activity of both COX-1 and COX-2. The inhibition of COX-2 activity decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever, and swelling while the inhibition of COX-1 is thought to cause some of the side effects of ibuprofen including GI. Nurofen Pain & Inflammation Relief Tablets 200mg provides effective relief from pain including headache, back pain, muscular pain, cold & flu pain and period pain. Nurofen provides effective pain relief for headaches, migraines, muscular pain, joint pain, period pain and more. On this page about Nurofen you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Nurofen exists to put people, not pain in charge of life. Building on years of research & innovation, Nurofen provides fast, effective relief from day-to-day pains so you can feel life to the fullest. Medical information for Nurofen including its dosage, uses, side, effects, interactions, pictures and warnings. Nurofen contains Ibuprofen, which has anti-inflammatory properties that helps relieve the symptoms of mild-moderate pain. Nurofen 200mg Tablets can be taken with water. Patient information for NUROFEN 400MG TABLETS Including dosage instructions and possible side effects.